One of my colleague (Tomislav Babic) has created a long but perfectly built article about creating an ASP.Net application.
He started from the database with Entity Framework, going on with Breeze.Net for the glue between client & server and close the article with Knockout JS & KOGrid for the client presentation layer.
If you want to learn from scratch how to setup a solution or if you want to discover some new frameworks, read it !

http://tomislavbabicnet.blogspot.com/2013/03/build-application-using-aspnet-mvc-4.html

Edit :
You will be able to manage some data with this new article :

http://tomislavbabicnet.blogspot.fr/2013/05/simple-crud-with-knockout-breeze-web.html